Rituximab, a chimeric mouse-human monoclonal antibody directed to the CD20 antigen expressed on pre-B lymphocytes and mature lymphocytes, causes a profound B-cell depletion.Due to its peculiar characteristics, this drug has been used to treat oncohaematological diseases, B cell-related autoimmune diseases, rheumatoid arthritis, and, more recently,
Novel 1, 2, 3-triazolic compounds derived from cytosine: Synthesis, spectroscopic characterization, in vitro antimicrobial activity and molecular docking studies
The development of novel antimicrobial drugs is crucial due to the increasing problem of antibiotic resistance.A new series of 1,4-disubstituted-1,2,3-triazole derivatives containing a cytosine moiety (3a, 3b, 3c and 3d) were synthesized using 1,3-dipolar equi-jec 6 cycloaddition in a mixture of ethanol and water under Cu(I)-catalyzed with N-alkyl:
RESPONSIBILITIES OF BUSINESS ACTORS ON FOOD SANITATION REVIEWED FROM CONSUMER PROTECTION LAW
The purpose of this research is to overcome the awareness problem of business actor, especially street vendors and consumer on the importance of hygiene and food sanitation, to identify how big the equi-jec 6 responsibility of business actors (Street Vendors) to products sold under the UUPK.This research is also a form of Research Grant for Beginne
Clinical analyses of ultrasound-guided nerve block in lower-extremity surgery: A retrospective study
Purpose: The purpose of this study is to examine the clinical effects and results of lower-extremity surgery under ultrasound-guided nerve block; time required for nerve block, anesthesia onset time, duration of anesthesia, duration of caruso rhodiola analgesia, tolerable tourniquet time, visual analog scale (VAS) satisfaction score, and anesthetic
Depression in the South African workplace
Depression is a common psychiatric disorder and can be costly, having a significant impact on the individual and employers.The South African Depression and Anxiety Group (SADAG) in partnership with HEXOR, with the support of Lundbeck, undertook research into depression in the workplace, because South African information is not available on this top